DIRE Score for Opioid Treatment

DIRE Score for Opioid Treatment
Diagnosis
Intractability
Risk (Psychological, Chemical Health, Reliability, Social Support)
Efficacy
DIRE Score: 4
Not a Good Candidate
Score <14: Not a good candidate for long-term opioid therapy.
Predicts compliance with opioid treatment for chronic noncancer pain.

Why Use

No prospective external validation exists that we are aware of, but the American Academy of Pain Medicine recommends the DIRE Score as a potential tool to assess abuse risk (strong recommendation, low quality evidence) ( Chou 2009 ).

Formula

Addition of the selected points: Variable Points Diagnosis Benign chronic condition, minimal objective findings, or no definite diagnosis (examples: fibromyalgia, migraine headaches, non-specific back pain) 1 Slowly progressive condition concordant with moderate pain or fixed condition with moderate objective findings (examples: failed back surgery syndrome, back pain with moderate degenerative changes, neuropathic pain) 2 Advanced condition concordant with severe pain with objective findings (examples: severe ischemic vascular disease, advanced neuropathy, severe spinal stenosis) 3 Intractability Few therapies tried; patient takes a passive role in pain management process 1 Most customary treatments have been tried but patient not fully engaged in pain management process or barriers prevent (examples: insurance, transportation, medical illness) 2 Patient fully engaged in spectrum of appropriate treatments but with inadequate response 3 Psychological risk Serious personality dysfunction or mental illness interfering with care (examples: personality disorder, severe affective disorder, significant personality issues) 1 Personality or mental health interferes moderately (examples: depression or anxiety disorder) 2 Good communication with clinic, no significant personality dysfunction or mental illness 3 Chemical health risk Active or very recent use of illicit drugs, excessive alcohol, or prescription drug abuse 1 Chemical coper (uses medications to cope with stress) or history of chemical dependence (CD) in remission 2 No CD history, not drug-focused or chemically reliant 3 Reliability risk History of numerous problems (medication misuse, missed appointments, rarely follows through) 1 Occasional difficulties with compliance but generally reliable 2 Highly reliable patient with meds, appointments, and treatment 3 Social support risk Life in chaos, little family support, few close relationships, loss of most normal life roles 1 Reduction in some relationships and life roles 2 Supportive family/close relationships, involved in work or school and no social isolation 3 Efficacy Poor function or minimal pain relief despite moderate to high doses 1 Moderate benefit with improved function in a number of ways (or insufficient information, hasn’t tried opioid yet, or very low doses/trial too short) 2 Good improvement in pain/function and quality of life with stable doses over time 3

Advice

Evidence on treating chronic noncancer pain is limited. Use best available evidence, alongside clinical judgment, in deciding whether to initiate opioids.

More Information

Interpretation: DIRE Score Candidacy for long-term opioid analgesia 7-13 Not a suitable candidate 14-21 Good candidate

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