Additional Nodal Metastasis Nomogram

Additional Nodal Metastasis Nomogram
Tumor Size
Tumor Grade
Lymphovascular Invasion
Multifocality
Number of Positive Sentinel Nodes
SLN Metastasis Size
Risk Score: –
Awaiting input
Select all criteria to compute the score.
Predicts likelihood of breast cancer with sentinel lymph node metastasis has also spread to additional lymph nodes.

Why Use

Many patients with a positive SLN will not have residual disease. This tool estimates the probability of additional non-SLN metastases, which may inform whether axillary lymph node dissection is warranted.

When to Use

Use in patients with invasive breast cancer with a positive sentinel lymph node (SLN) when deciding next steps in management.

Formula

Multivariate nomogram, with assigned points to 8 criteria.

Pearls / Pitfalls

Pathology techniques and systemic therapy have evolved since this tool was developed, which can shift baseline risks and affect calibration in modern cohorts. External validations show moderate discrimination and variable calibration; reliability of nomograms for clinical use has been questioned.

Advice

Use results with multidisciplinary input to determine appropriate axillary management, which may include: Adjuvant chemotherapy. Regional radiotherapy. Targeted axillary dissection. Axillary lymph node dissection. Please review your local medical society guidelines for additional management recommendations, such as the American Society of Breast Surgeons and the National Comprehensive Cancer Network .

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