Risk of Malignancy Index (RMI) for Ovarian Cancer
RMI Calculator
Multilocular Cyst
Solid Areas
Bilateral Lesions
Ascites
Intra-abdominal Metastases
Menopausal Status
U/mL
RMI Score:
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Predicts risk that an adnexal mass is malignant.
Formula
RMI = menopausal status x ultrasound score x serum CA-125, U/mL Where menopausal status and ultrasound score are as follows: Variable Points Ultrasound features Multiloculated cysts 1 if 0-1 present 3 if ≥2 present Solid areas Bilateral lesions Ascites Intra-abdominal metastases Menopausal status* Premenopausal or perimenopausal 1 Postmenopausal 3 *Postmenopausal status = >1 year of amenorrhea or age ≥50 years if patient is status post hysterectomy.
Pearls / Pitfalls
Requires CA-125 level to calculate, which may not otherwise be obtained.
Advice
Consider further workup in patients with elevated RMI.
More Information
Interpretation: RMI Risk of malignancy ≤200 Low >200 High* *71% sensitive and 92% specific for ovarian cancer.