Revised Natural History Model for Primary Sclerosing Cholangitis
Revised Mayo PSC Risk Calculator
years
mg/dL
U/L
g/dL
History of Variceal Bleeding
Mayo PSC Risk Score:
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Estimates survival from primary sclerosing cholangitis.
Why Use
The Revised Natural History Model for PSC is a convenient and simple scoring system.
When to Use
Patients with known primary sclerosing cholangitis.
Formula
Risk Score = 0.03*(age [y]) + 0.54*log e (bilirubin [mg/dL]) + 0.54*log e (aspartate aminotransferase [U/L]) + 1.24*(variceal bleeding [Y=1,N=0]) - 0.84*(albumin [g/dL])
Pearls / Pitfalls
The Revised Natural History Model (Mayo Score) for Primary Sclerosing Cholangitis (PSC) provides a standardized assessment to help predict survival and transplant need. It does not require require histology or liver biopsy, making it a useful, non-invasive test.
Advice
The Revised Natural History Model for PSC is a convenient and simple scoring system.
More Information
Scores ≤0 - low risk group. Scores 0-2 - intermediate risk group. Scores >2 - high risk group.