Pediatric NIH Stroke Scale (NIHSS)
Why Use
Pediatric stroke is relatively uncommon, but remains an important cause of morbidity and mortality. Adult stroke scales have limited sensitivity when translated to a pediatric population (62-67% sensitivity according to one analysis by Mackay et al, 2016 ). PedNIHSS is up to 87% sensitive ( Beslow 2012 ). Determines the severity of pediatric stroke and can be trended over time to assess recovery. Initial PedNIHSS may be predictive of future disability at 90 days.
When to Use
Pediatric patients 2-18 years old with clinical and radiologic signs of acute ischemic stroke.
Formula
Pearls / Pitfalls
The presentation of stroke in younger children can be subtle and include altered mental status, depressed level of consciousness, and apneas, among others. Posing the questions and tasks in the PedNIHSS as a game may aid motivation in patients, especially younger children. The developmental age of the child in their pre-morbid state must be considered. Consultation with the child’s primary pediatrician may be useful in estimating the child’s developmental age; performing a validated developmental screening tool using parental recall may also be helpful. Assessment of muscle strength in uncooperative patients may be made by careful observation of spontaneous movement, or elicited movement, as compared to a developmentally and neurologically appropriate child of the same age as the patient being evaluated.
Management
This score has not been validated in hemorrhagic stroke; in such cases, the need for emergent neurosurgical consult is clear. Given the overall rarity of pediatric stroke, the benefit of tPA is not well defined in the literature, emphasizing the importance of expert consultation.
Critical Actions
Children with sickle cell disease presenting with acute ischemic stroke will likely benefit from emergent blood transfusion to reduce hyperviscosity caused by sickled cells. Early consultation with a pediatric hematologist is recommended in addition to child neurology consult.
Advice
Pediatric stroke is overall rare, and the true predictive value of the PedNIHSS is subject to change as the scale continues to be studied. Retrospective application of the PedNIHSS has been shown to be valid and reliable in one cross-sectional study (see Beslow 2012 ).
More Information
Interpretation: Higher scores correspond with worse prognosis. Repetition test: Ask patient to repeat the following statements: Reading test: Ask patient to read the following statements: Naming test: Ask patient to name the following items: Fluency test: Ask patient to describe what he/she sees: Figure from Ichord 2011 .