Blood Volume Calculation
Blood Volume Calculator
Patient Type
kg
Blood Volume:–
mL
Estimated Blood Volume
–
Calculates total blood volume, red blood cell volume, and plasma volume.
When to Use
Use when blood volumes are needed (e.g. RBC exchange, plasma exchange, coagulation factor drug dosing, RhIG dosing calculations).
Formula
Total blood volume, L (adults and children ≥25 kg) Male = [ 0.3669 × (height, m) 3 + 0.03219 × (weight, kg) + 0.6041 ] Female = [ 0.3561 × (height, m) 3 + 0.03308 × (weight, kg) + 0.1833 ] Total blood volume, mL (neonates and children <25 kg) = weight, kg × Y, where Y is as follows: Preterm neonate: 100 mL/kg Term neonate: 85 mL/kg Infant aged 1-4 months: 75 mL/kg Child <25 kg: 70 mL/kg RBC volume, mL = total blood volume, mL × hematocrit / 100 Plasma volume, mL = total blood volume, mL × ( 1 – hematocrit / 100 ) Example: adult male, height = 180 cm, weight = 70 kg, Hct = 25% Total blood volume, L = [ 0.3669 × (height, m) 3 + 0.03219 × (weight, kg) + 0.6041 ] = [ 0.3669 × (180 / 100) 3 + 0.03219 × (70) + 0.6041 ] = 2.1398 + 2.2533 + 0.6041 = 5.0 L (4,997 mL) Red blood cell volume, mL = (4,997 mL) × (25% / 100) = 4,997 mL × 0.25 = 1,249 mL Plasma volume, mL = 4,997 mL × [1 - (25% / 100)] = 4,997 mL × 0.75 = 3,748 mL
Pearls / Pitfalls
Total blood volume is calculated using Nadler’s equation.
Advice
If dosing for RBC exchange, use in conjunction with Sickle Cell RBC Exchange Volume .